Understanding the Molecular Epidemiology of the Footrot Pathogen Dichelobacter nodosus To Support Control and Eradication Programs

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Understanding the molecular epidemiology of the footrot pathogen Dichelobacter nodosus to support control and eradication programs.

The Gram-negative anaerobe Dichelobacter nodosus is the primary etiologic agent of ovine footrot. Few studies of the genetic diversity and epidemiology of D. nodosus have been done, despite the economic cost and welfare implications of the disease. This study examined a large collection of Australian isolates; 735 isolates from footrot-infected sheep from 247 farms in Western Australia (WA) wer...

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Genomic Evidence for a Globally Distributed, Bimodal Population in the Ovine Footrot Pathogen Dichelobacter nodosus

UNLABELLED Footrot is a contagious, debilitating disease of sheep, causing major economic losses in most sheep-producing countries. The causative agent is the Gram-negative anaerobe Dichelobacter nodosus. Depending on the virulence of the infective bacterial strain, clinical signs vary from a mild interdigital dermatitis (benign footrot) to severe underrunning of the horn of the hoof (virulent ...

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Virulence regions and virulence factors of the ovine footrot pathogen, Dichelobacter nodosus.

Ovine footrot is a debilitating and highly infectious disease that is primarily caused by the Gram-negative, anaerobic bacterium Dichelobacter nodosus. The major antigens implicated in virulence are the type IV fimbriae and extracellular proteases. The fimbriae show sequence and structural similarity to other type IV fimbriae, this similarity extends to genes that are involved in fimbrial bioge...

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Survival of the ovine footrot pathogen Dichelobacter nodosus in different soils.

Dichelobacter nodosus (D. nodosus) is the causative agent of footrot in sheep; one of the most important health and welfare issues of sheep worldwide. For control programmes to be effective, it is essential that the transmission cycle of D. nodosus is understood and bacterial reservoirs in the environment are better defined. This study evaluated the survival of D. nodosus in different soils usi...

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Isolation and Characterisation of Dichelobacter Nodosus from Footrot Infected Sheep in Malaysia

Introduction Dichelobacter nodosus is the causative agent of severe footrot, a contagious debilitating disease which affects ruminants particularly sheep and goats. The disease is characterised by separation of the hom of the hoof from the underlying soft tissues resulting in lameness, loss of body condition and reduced wool production (Rood et al. 1996). The first case of footrot in Malaysia w...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2010

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.01355-09